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The Science of Gratitude: How a Simple Practice Can Rewire Your Brain and Support Whole-Person Healing

Discover how daily gratitude journaling can rewire your brain, enhance mental and physical health, and support emotional resilience-rooted in the science of neuroplasticity and whole-person care.

BRAIN HEALTH

Natalie Nedeau, APRN, FNP-C

4 min read

Today I am Grateful book
Today I am Grateful book

In the midst of daily life, it’s easy to overlook the quiet moments that offer meaning, comfort, or joy. But what if tuning into those moments—intentionally—could begin to change the way your brain is wired?

At Libellula Integrative Care, we often say healing doesn’t just happen in the body-it begins in the mind. One of the most powerful tools to support this process is also one of the simplest: a daily gratitude journaling practice.

Gratitude Journaling: A Small Habit With Big Potential

Gratitude journaling is the intentional act of writing down what you’re thankful for—big or small. These might include a meaningful conversation, the warmth of sunlight, or simply making it through a hard day.

Though simple, this practice taps into one of the brain’s most adaptive capacities—neuroplasticity. This allows the ability of the brain to change in response to experience and intentional repetition. Over time, it can literally reshape how you think and feel.

Rewiring the Brain Through Gratitude

When you consistently focus on gratitude, you activate neural pathways associated with positive emotion, empathy, and emotional regulation-particularly in the medial prefrontal cortex (Kini et al., 2016). The more these pathways are activated, the stronger they become— making it easier for your brain to notice the good, respond with clarity, and build resilience.

This is the foundation of neuroplasticity. Just like physical movement can strengthen muscles, gratitude strengthens emotional and cognitive flexibility. In this way, journaling gratitude becomes more than a reflective tool—it becomes a daily act of transformation.

What the Research Shows

Improves Mental Health
People who practice gratitude regularly report fewer symptoms of depression and anxiety. A landmark study by Emmons & McCullough (2003) found that weekly gratitude journaling improved optimism, physical well-being, and overall life satisfaction.

Enhances Emotional Resilience
Gratitude helps regulate the stress response, calming the nervous system and reducing levels of cortisol. Studies have shown it can help people process trauma and build psychological resilience (Wood et al., 2007).

Supports Restorative Sleep
Reflecting on positive moments before bed reduces intrusive thoughts and supports deeper, more restful sleep. Even 15 minutes of gratitude journaling at night has been shown to improve sleep quality (Wood et al., 2009).

Boosts Physical Health
Gratitude has been associated with lower blood pressure, improved heart rate variability, and reduced inflammation. In patients with chronic illness, practicing gratitude has even been linked to improved health behaviors and outcomes (Mills et al., 2015).

Why a Daily Practice Matters

Neuroplasticity is driven by repetition. The more often you activate a neural pathway, the stronger it becomes. Gratitude journaling done daily—even for just a few minutes-teaches your brain to recognize what’s going well, even amidst stress or uncertainty.

Over time, this subtle shift can ripple outward: improving your mood, sharpening your focus, and enhancing your capacity for connection and joy.

How to Get Started
  • Choose a consistent time: Many people journal at night to help wind down, but morning reflection can also set a grounded tone for the day.

  • Keep it brief: A list of three things, or just a few sentences, is enough.

  • Be specific: “Grateful for coffee” becomes more meaningful as “Grateful for the quiet moment drinking coffee before the house woke up.”

  • Use a dedicated notebook or app: Make the practice easy and enjoyable.

Gratitude as a Healing Tool

At Libellula Integrative Care, we look beyond symptoms-we ask what supports vitality at every level. Gratitude journaling is one such support—it’s free, accessible, and grounded in neuroscience. It doesn’t require perfection or positivity, only presence.

When you write down what you’re grateful for, you're not ignoring what’s hard. You’re creating space for what else is true. And from that space, healing becomes not only possible, but sustainable.

Start Your Healing Journey

Healing begins in small moments-like a breath, a shift in perspective, or a few words of gratitude.
At Libellula Integrative Care, we believe these daily rituals are just as vital as lab results or protocols. If you’re ready to explore a more grounded, whole-person path to wellness, we’re here to support you.

Schedule your consultation and let’s begin this journey, together.


References:

Emmons, R. A., & McCullough, M. E. (2003). Counting blessings versus burdens: An experimental investigation of gratitude and subjective well-being in daily life. Journal of Personality and Social Psychology, 84(2), 377–389. https://doi.org/10.1037/0022-3514.84.2.377

Kini, P., Wong, J., McInnis, S., Gabana, N., & Brown, J. W. (2016). The effects of gratitude expression on neural activity. NeuroImage, 128, 1–10. https://doi.org/10.1016/j.neuroimage.2015.12.040

Mills, P. J., Redwine, L., Wilson, K., Pung, M. A., Chinh, K., Greenberg, B. H., & Lunde, O. (2015). The role of gratitude in spiritual well-being in asymptomatic heart failure patients. Spirituality in Clinical Practice, 2(1), 5–17. https://doi.org/10.1037/scp0000050

Wood, A. M., Froh, J. J., & Geraghty, A. W. A. (2010). Gratitude and well-being: A review and theoretical integration. Clinical Psychology Review, 30(7), 890–905. https://doi.org/10.1016/j.cpr.2010.03.005

Wood, A. M., Joseph, S., Lloyd, J., & Atkins, S. (2009). Gratitude influences sleep through the mechanism of pre-sleep cognitions. Journal of Psychosomatic Research, 66(1), 43–48. https://doi.org/10.1016/j.jpsychores.2008.09.002

Wood, A. M., Maltby, J., Gillett, R., Linley, P. A., & Joseph, S. (2008). The role of gratitude in the development of social support, stress, and depression: Two longitudinal studies. Journal of Research in Personality, 42(4), 854–871. https://doi.org/10.1016/j.jrp.2007.11.003